http://potentcompoundsafety.com Mon, 18 Jan 2016 21:39:37 +0000 en-US hourly 1 http://wordpress.org/?v=4.2.7 no http://potentcompoundsafety.com/wp-content/plugins/powerpress/rss_default.jpg http://potentcompoundsafety.com New Podcast is up: The Mystery of Cytotoxic Compounds http://potentcompoundsafety.com/2016/01/cytotoxic-compounds.html http://potentcompoundsafety.com/2016/01/cytotoxic-compounds.html#comments Mon, 18 Jan 2016 21:39:37 +0000 http://potentcompoundsafety.com/?p=2634 Our new podcast on “Mystery of Cytotoxic Compounds” is now posted on the affygility.com website. In this podcast, Dr. Joe Nieusma and Dean Calhoun, CIH discuss the following:

  • What is a “cytotoxic compound?”
  • How are cytotoxic compounds determined?
  • What are examples of traditional cytotoxic compounds?
  • Are the terms “cytotoxic” and “genotoxic” synonymous?
  • Do I need a dedicated manufacturing facility or equipment for cytotoxic compounds?
  • Can an occupational exposure limit (OEL) and acceptable daily exposure (ADE/PDE) value be established for a cytotoxic compound?

In addition, Dean Calhoun discusses events and happenings that are related to environmental, health, and safety in the life sciences industry. To listen to this podcast, click on the link above or below.

 

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http://potentcompoundsafety.com/2016/01/cytotoxic-compounds.html/feed 0 Our new podcast on "Mystery of Cytotoxic Compounds" is now posted on the affygility.com website. In this podcast, Dr. Joe Nieusma and Dean Calhoun, CIH discuss the following: What is a "cytotoxic compound?" How are cytotoxic compounds determined? Our new podcast on "Mystery of Cytotoxic Compounds" is now posted on the affygility.com website. In this podcast, Dr. Joe Nieusma and Dean Calhoun, CIH discuss the following: What is a "cytotoxic compound?" How are cytotoxic compounds determined? What are examples of traditional cytotoxic compounds? Are the terms "cytotoxic" and "genotoxic" synonymous? Do I need a dedicated manufacturing facility or equipment for cytotoxic compounds? Can an occupational exposure limit (OEL) and acceptable daily exposure (ADE/PDE) value be established for a cytotoxic compound? In addition, Dean Calhoun discusses events and happenings that are related to environmental, health, and safety in the life sciences industry. To listen to this podcast, click on the link above or below.   NO AUTHOR no 27:58
Affygility Solutions on SnapChat http://potentcompoundsafety.com/2016/01/affygility-solutions-snapchat.html http://potentcompoundsafety.com/2016/01/affygility-solutions-snapchat.html#comments Wed, 13 Jan 2016 17:16:02 +0000 http://potentcompoundsafety.com/?p=2631 Getting ready to starting posting some serious sound-bites of EHS knowledge on SnapChat. Will be cover the basics of environmental, health and safety in the life science industry, as well as fun stuff regarding the world-wide travels of an EHS professional. Add Affygility through the username affygility or take a picture of the Snap code below:

affygility-snapchat-code

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Affygility Solutions encrypts its entire website for all visitors http://potentcompoundsafety.com/2015/07/affygility-solutions-encrypts-website-visitors.html http://potentcompoundsafety.com/2015/07/affygility-solutions-encrypts-website-visitors.html#comments Mon, 13 Jul 2015 02:56:07 +0000 http://potentcompoundsafety.com/?p=2623 Beginning today, Affygility Solutions will encrypt its entire website, making it extremely difficult for hackers, governmental agencies, and others to track the reading habits of people visiting the site. The added security will apply to all pages on the affygility.com domain.

“Here at Affygility Solutions, security and privacy for our site visitors has always been a top priority” says Dean M. Calhoun, CIH, President and CEO of Affygility Solutions “and while, our e-commerce portions of the site have always been encrypted, we recognize that many of our visitors are frequent business travelers and are accessing our site through airport and public WiFi hotspots. We want our visitors to know that their visits to our site, no matter where they connect, are protected.”

While encryption has long been the standard for finance and e-commerce sites, Affygility Solutions, as an industry leader, is the first environmental, health, and safety consulting firm to roll-out encryption for all its site visitors.

Most browsers will note the added security with a display icon depicting a small lock, in the web address bar. The secure affygility.com site will also begin with “https” instead of the former “http.” The type of encryption used by Affygility Solutions is known as SSL (secure sockets layer) which establishes a private connection between the website and the user, making spying or hijacking extremely difficult.

This encryption technology also has the potential to make online monitoring more difficult for governments with high levels of censorship and surveillance. When visitors go to a site using SSL, someone monitoring their traffic will only see the domain that they are visiting – not the specific page. Since Affygility Solutions has potent compound safety clients in over 30 different countries, this is of growing importance in protecting the privacy of our clients’ information.

For further information, please contact Affygility Solutions.

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Upcoming potent compound safety presentation by Affygility Solutions http://potentcompoundsafety.com/2015/06/potent-compound-safety-presentation-affygility-solutions.html http://potentcompoundsafety.com/2015/06/potent-compound-safety-presentation-affygility-solutions.html#comments Sun, 28 Jun 2015 23:58:07 +0000 http://potentcompoundsafety.com/?p=2619 The following is a list of the upcoming potent compound safety presentations by Affygility Solutions:

  • 4th Annual HPAPI Conference, Boston, MA, Monday, July 13th, 2015: Risk Management & Industrial Hygiene: Preventing Cross Contamination & Employee Exposures In The Context Of HPAPIs
  • CPhI Worldwide, Madrid, Spain, Tuesday, October 13th, 2015: Safe Handling of Potent Compounds.
  • 2015 ISPE Annual Meeting, Philadelphia, PA. Monday, November 9th, 2015: The Future of Pharma Manufacturing – The Next 100 Years

If you’re attending any of these conferences, please feel free to come up and introduce yourself. If you would like to schedule a private meeting, please complete the “contact us” form on our main website.

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Attending AIHce 2015? Follow Affygility on Twitter or Instagram http://potentcompoundsafety.com/2015/05/aihce-2015-affygility-twitter-instagram.html http://potentcompoundsafety.com/2015/05/aihce-2015-affygility-twitter-instagram.html#comments Wed, 13 May 2015 01:07:13 +0000 http://potentcompoundsafety.com/?p=2610 Attending the American Industrial Hygiene Conference and Exposition (AIHce) 2015 in Salt Lake City, May 30th through June 4th? Follow Affygility Solutions on Twitter or Instagram for deets on #secretbeerparty2.0. Want advance notice of the location? Then follow affygility on Snapchat (works on smartphones only, no desktop version). Don’t know how to use Snapchat, then go here: Snapchat Basics. This year’s party plans to be better than ever. If you don’t follow, you won’t know. Hook up with either Peter Burke or Dean Calhoun during the conference for a wristband. Time and location to be announced later. Wristbands only.

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Get your FREE ebook: Potent Compound Safety Handbook – A Guide to Working with Potent Compounds http://potentcompoundsafety.com/2015/04/potent-compound-safety-handbook-guide-working-potent-compoundsaff.html http://potentcompoundsafety.com/2015/04/potent-compound-safety-handbook-guide-working-potent-compoundsaff.html#comments Sat, 25 Apr 2015 16:24:31 +0000 http://potentcompoundsafety.com/?p=2600 Affygility Solutions is pleased to announce the availability of its latest FREE eBook: Potent Compound Safety Handbook – A Guide to Working with Potent Compounds. In this 18-page handbook in pdf format, we will cover the following topics:

  • The definition of “What is a Potent Compound?”
  • Getting your potent compound safety program started
  • Determining occupational hazard categories
  • Ten myths regarding PDEs, ADEs, and OELs
  • The future of OELs

To download this FREE eBook in pdf format click here.

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Affygility Solutions publishes IFTTT recipe for OEL Fastrac notifications http://potentcompoundsafety.com/2015/04/affygility-solutions-publishes-ifttt-recipe-oel-fastrac-notifications.html http://potentcompoundsafety.com/2015/04/affygility-solutions-publishes-ifttt-recipe-oel-fastrac-notifications.html#comments Mon, 13 Apr 2015 00:52:52 +0000 http://potentcompoundsafety.com/?p=2596 Now stay up to date and get instantly notified by email of the latest OEL Fastrac with ADE monographs that has been posted to the oelfastrac.com site! Affygility Solutions has published an IFTTT (If-this-than-that) recipe to make it easy. Just go to the link below to get the recipe:

https://ifttt.com/recipes/275270-sends-an-oel-fastrac-update-to-your-email

]]> http://potentcompoundsafety.com/2015/04/affygility-solutions-publishes-ifttt-recipe-oel-fastrac-notifications.html/feed 0 OEL Fastrac catalog listing now available as a RSS feed http://potentcompoundsafety.com/2015/03/oel-fastrac-rss-feed.html http://potentcompoundsafety.com/2015/03/oel-fastrac-rss-feed.html#comments Mon, 30 Mar 2015 02:12:40 +0000 http://potentcompoundsafety.com/?p=2585 Affygility Solutions is pleased to announce that its OEL Fastrac catalog listing is now available as a RSS (Really Simple Syndication) feed. Listed below is an example of the feed displaying that latest six occupational exposure limit (OEL) with ADE monographs. Click on the compound name heading to go directly to the specific OEL/ADE monograph product page.

  • Rilmenidine


    Rilmenidine is a centrally acting drug used for high blood pressure. It is well tolerated with a low incidence of adverse effects and effective, alone or in combination with other blood pressure therapeutics, for the treatment of mild-to-moderate high blood pressure in most patient populations including high-risk patients.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Rilmenidine is available for purchase for $597 USD.

  • Norethindrone


    Please note, this OEL/ADE monograph also applies to Norethindrone acetate (CAS RN 51-98-9). Norethindrone is indicated for the treatment of lack of menstrual period, dysfunctional uterine bleeding and endometriosis.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Norethindrone is available for purchase for $597 USD.

  • Olopatadine


    Please note, this OEL/ADE monograph also applies to Olopatadine HCl (CAS RN 140462-76-6). Olopatadine is indicated for the treatment of allergies and seasonal allergic runny nose.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Olopatadine is available for purchase for $597 USD.

  • Sodium Picosulfate


    Sodium picosulfate is a laxative used to prepare the bowel for a colonoscopy. Citric acid and magnesium oxide react in solution to create magnesium oxide, an osmotic laxative that retains water in the gastrointestinal tract. Sodium picosulfate is hydrolyzed by colonic bacteria to bis-(p-hydroxy-phenyl)-pyridyl-2-methane, which stimulates colonic peristalsis by direct action on colonic mucosa. When administered together as a precolonoscopy preparation, the stimulant laxative and osmotic laxative effects of sodium picosulfate and magnesium citrate, respectively, produce a purgative effect and (with consumption of additional fluids) watery diarrhea.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Sodium Picosulfate is available for purchase for $597 USD.

  • Tiaprofenic Acid


    Tiaprofenic acid, a non-steroidal anti-inflammatory drug (NSAID), is used for rheumatoid or osteoarthritis. Tiaprofenic acid is a nonsteroidal anti-inflammatory agent with potent pain relieving, fever reducing and anti-inflammatory properties. Tiaprofenic acid is a potent inhibitor of prostaglandin synthesis. This inhibition primarily occurs in the cyclo-oxygenase pathway, which transforms arachidonic acid into endoperoxides and prostaglandins.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Tiaprofenic Acid is available for purchase for $597 USD.

  • Valproic acid


    Valproic acid is indicated to treat absence seizure, manic bipolar disorder, complex partial seizure , and to prevent migraines. Valproic acid is an antiepileptic agent with unknown therapeutic mechanism of action, although, it is believed to exert its effect by increasing the concentrations of gammaaminobutyric acid (GABA) in the brain.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Valproic acid is available for purchase for $597 USD.

If you wish to add the feed to a feed reader, here’s the link: http://affygility.com/oel/feed.xml

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Thoughts and musings from the 2015 NAEM EHS and Sustainability Software Conference http://potentcompoundsafety.com/2015/03/ehs-sustainability-software-conference.html http://potentcompoundsafety.com/2015/03/ehs-sustainability-software-conference.html#comments Sun, 01 Mar 2015 21:15:04 +0000 http://potentcompoundsafety.com/?p=2563 Just finished up a nice couple of days last week in Tampa, Florida at the National Association for Environmental Management (NAEM) EHS and Sustainability Software conference. The event was held at the Westin Hotel, Harbour Island which was a fantastic location, and considering the horrific weather that my colleagues have been experiencing in the northeast, I’m sure the warmer weather was a welcomed sight. This has been at least my fourth such event, and as always, the NAEM staff had a well-run event with no hiccups. The general format of the conference over the course of two-days was an opening talk/keynote each morning, then a series of “demos” throughout the day. There was a pre-conference workshop the day before the main EHS software conference, but I was unable to attend.

The demos were performed by actual customers of the systems and repeated at least once during the day. So, if you planned it right, you could catch a glimpse of the EHS software systems you wanted to see.

Overall Thoughts and Musings

Based on the sessions that I attended, here’s my thoughts and musings:

  • During the official welcome and introductions, NAEM Program Director, Mike Mahanna encourage attendees to use Twitter during the event. However, post-conference analysis of the Twitter #NAEMSoftware stream revealed 18 tweets using this hashtag, with myself (@affygility) being half of them. This clearly needs to change and every vendor should have been using Twitter to drive traffic to their booth. Take a suggestion from the tech conferences, assign #hashtags to each session and have it on the opening slide for the session. It’s a way for the presenters to collect feedback on the specific session.
  • If you’re going to call them “demos” then do real demos. Many of the sessions were the presenters talking about their company and the process that they went through to get their EHS software up and running. Then once it came down to the actual software demo, in many cases, they were screenshots embedded within PowerPoint slides. Unfortunately, when demos are run this way, it’s difficult to tell how efficiently the user-interface (UI) works and the speed of the system (a well-designed system should work in the worst of bandwidth conditions). In addition, in some cases, it’s apparent that it’s a staged presentation and they are showing the “best” looking UIs. If possible they should follow the format of the “Demo organization.” Live software with real internet connectivity and no PowerPoint, just demo. Forget the introductory slides with telling everyone how many facilities, employees, etc. that you have in your organization. You can verbally tell us that information, but we don’t need 10 minutes of it.
  • This is largely a competitive intelligence event. The majority of the attendees are EHS software providers and consultants checking out their competitors applications. No pretense on my part, that’s exactly why I attended the EHS software event. Yes, there are some actual potential customers, but they are few and far between and are typically ones that are unhappy with their current system.
  • The twisty folder interface seems to be persistent. Maybe this is a leftover from the days of Lotus Notes or the familiarity with Microsoft Outlook folders, but this UI is getting stale. In addition, with the importance of mobile usage growing and growing, this is not going to work in the long-term. Let’s get rid of that UI and think of something different.
  • There’s a real dichotomy out there in that EHS leadership keeps demanding an one-stop shop “enterprise” system where all EHS data is gathered, with totally customizable reporting, that mimics their current form system. And, by the way, it has to be intuitive, easy to use, and mobile.  Sorry people, that’s an impossible set of requirements, and you’re smoking weed if you think it’s going to happen.
  • There continues to be a discussions on mobile, but in the sessions that I attendee it’s quite clear that few vendors understand the unique UI/UX requirements of mobile. Take a look at well designed consumer apps like Foursquare, Instagram, EpicMix, and SnapChat. BTW – you can follow me on SnapChat @affygility
  • Based on the sessions I saw, and the event I attended two years ago, there is really nothing disruptive coming down the pipe. More of the same, same old stuff, with no integration with the Internet of Things technologies, no talk of gamification to drive user engagement, and still a heavy reliance on time-consuming, manual data entry. EHS software vendors need to start thinking differently about the future.

Overall thoughts – well organized event, great location, but the EHS software industry is struggling to find something new to talk about. Tweet me your thoughts @affygility or visit our site at http://affygility.com

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Follow Affygility Solutions on SnapChat. http://potentcompoundsafety.com/2015/02/follow-affygility-solutions-snapchat.html http://potentcompoundsafety.com/2015/02/follow-affygility-solutions-snapchat.html#comments Mon, 23 Feb 2015 02:50:07 +0000 http://potentcompoundsafety.com/?p=2557 Want near real-time updates on what’s going on with the field of EHS in the pharmaceutical industry? Then add us as a friend on SnapChat. Don’t have a clue about SnapChat. Well, you’re likely over 25 years old, but here’s the beginner’s guide to SnapChat by Mashable. Once you read through this guide then simply point your camera at the image below and you’ll find Affygility Solutions.

affygility snapchat

 

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