http://potentcompoundsafety.com Mon, 25 Jul 2016 01:43:25 +0000 en-US hourly 1 http://wordpress.org/?v=4.2.9 http://potentcompoundsafety.com/wp-content/plugins/powerpress/rss_default.jpg http://potentcompoundsafety.com Snapchat for Environmental Health and Safety (EHS) http://potentcompoundsafety.com/2016/07/snapchat-environmental-health-safety-ehs.html http://potentcompoundsafety.com/2016/07/snapchat-environmental-health-safety-ehs.html#comments Mon, 25 Jul 2016 01:43:25 +0000 http://potentcompoundsafety.com/?p=2643 As new technologies emerge, the approach to marketing and how business is conducted has changed.  In today’s mobile-first society, there are now countless opportunities for making connections and reaching a larger audience; and within the past decade, it is becoming quite common for businesses to reach their audiences through the use of social media.

The Evolution and Growth of Snapchat

Since 2011, Snapchat  has been a mobile only social media platform that has really changed the game for marketing. With Snapchat a business is able to produce daily stories and interact with potential clients with ease and efficiency. Snapchat allows for quick and immediate connections with a large span of users at one time. As of 2016, 100 million people use Snapchat every day. As a business that uses Snapchat this allows for the company to reach out to more users with quick information and draw more traffic towards the business. Snapchat now has more users that Twitter, and the videos on Snapchat surpass those that are watched on Facebook. This makes Snapchat one of the most influential social media platforms in 2016.

By allowing users to broadcast events such as launches of new products and information, conferences or company gatherings. Snapchat provides a business with the ability to teach and entertain both current and prospective clients. Through this type of “storytelling” social media, a business is given a personality which makes it easier for clients to connect with, relate too and overall trust. Through storytelling clients are able to feel they are a part of the brand and connect on a much deeper level. Through partnerships with social media influencers, Snapchat has the ability for people to work together while addressing relevant issues and marketing their product. For big brands such as Red Bull and Huffington Post, Snapchat takeovers are important to reach out to creative and interesting people to take over their Snapchat account for special events and entertain the audience in a new way. This is useful both to the company and the people doing the takeover to work together to create web traffic and brand awareness for both parties.

Accounts to follow that perform an excellent job of using Snapchat as a marketing method include:

Applying Snapchat to the Field of Environmental, Health and Safety

While the field of environmental health and safety is one area of business that seems to be lagging behind in the adoption of Snapchat, this presents an opportunity. If applied correctly, Snapchat can be used successfully by any type of business. Snapchat for environmental health and safety can be utilized in the following ways:

  • Provide short demonstrations of new products and equipment;
  • Provide behind the scenes sneak peeks into conferences and events;
  • Present interviews with clients about their projects;
  • Introduce new employees and give a face to the business;
  • Provide short educational overviews into the field of environmental, health and safety

For more examples and techniques, add Affygility on Snapchat.

snapchat-affygility-environmental-health-safety

Sources:

“The Snapchat Statistics Every Marketer Needs To Know”. Mediakix.com

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Opinion: Potent Compound Manufacturing – The Chicken or the Egg Problem http://potentcompoundsafety.com/2016/06/potent-compound-manufacturing.html http://potentcompoundsafety.com/2016/06/potent-compound-manufacturing.html#comments Tue, 28 Jun 2016 22:49:27 +0000 http://potentcompoundsafety.com/?p=2639 So your company has years of experience at being a pharmaceutical manufacturer. However, recently your business development (BD) professionals have been receiving requests that go something like this, “Can you handle potent compounds?” or “Can you handle Category 4 or 5 potent compounds?” Not wanting to say “no” and turn down potential business opportunities, the BD professionals consult with the management team. Then usually members of the management team gather around the table and discuss the market opportunities, the competition, the impact on existing operations, and what additional safety precautions or engineering controls are needed. Everyone is excited and wants to pursue this “opportunity” further. This is usually when Affygility Solutions receives a phone asking the question, “What do I need to do to handle ‘potent’ compounds?” Of course, without knowing a lot more about your goals and operations, that’s a very risky question for us to answer.

Potent Compound Manufacturing is a chicken or the egg problem

Prior to taking on projects that involve the handling of potent compounds that are Category 3 and up, it’s going to take an investment. However, often companies are willing to make the investment without having a sign contract for the project – and, no reputable client is going to sign a contract for their project without knowing that you are equipped to properly handle their potent compound. Hence, the chicken or the egg problem – which comes first? No sign contract = no investment, no investment = no sign contract.

Understand all the Business Dynamics of Handling Potent Compounds

Prior to just diving head first into the dark, murky waters of highly potent compounds (generally Category 3, 4, or 5) educate yourself in the business dynamics of potent compounds. Proper handling of potent compounds will impact almost every department in your company. Discuss amongst your team how it will impact the following:

  • How will you effectively market “potent compound manufacturing services?”
  • How will you train your business development, sales staff and operational personnel in this area of expertise? You want to make sure that you can deliver on any promises.
  • Are you willing to make the long-term capital investments in facilities, air-handling, and engineering controls to safely manufacture potent compounds? In addition, there will be ongoing operational costs in categorizing potent compounds, training employees, containment verification studies, maintenance of engineering controls, industrial hygiene monitoring, and “disposables.”
  • How will you on-board and categorize new compounds? How will you make “go” or “no-go” decisions? Just as important as it is to know what types of compounds you can handle, it’s equally as important to know what compounds or project are out of your league.
  • Once a proposal has been accepted, what type of risk-assessments will you perform for each step of the project?
  • How will you implement permissible daily exposure (PDE) or acceptable daily exposure (ADE) limits into your cleaning validation requirements? Note, depending upon the PDE/ADE value, it may require that you develop more sensitive and/or product-specific analytical methods.
  • Understand how all the above factors will impact the cost of a project. How will these costs be captured and passed onto the customer?
  • And, many others.

It takes a Commitment – both Financially and Operationally

No matter how much you debate above questions, at some point it is going to take a commitment, both financially and operationally. To do so otherwise is going to not be of value to the company or the client. Just “dabbling” in potent compound manufacturing has a low probability of providing the expected financial return.

If you would like to request an on-site gap assessment of your potent compound safety program, please contact Affygility Solutions.

 

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New Podcast is up: The Mystery of Cytotoxic Compounds http://potentcompoundsafety.com/2016/01/cytotoxic-compounds.html http://potentcompoundsafety.com/2016/01/cytotoxic-compounds.html#comments Mon, 18 Jan 2016 21:39:37 +0000 http://potentcompoundsafety.com/?p=2634 Our new podcast on “Mystery of Cytotoxic Compounds” is now posted on the affygility.com website. In this podcast, Dr. Joe Nieusma and Dean Calhoun, CIH discuss the following:

  • What is a “cytotoxic compound?”
  • How are cytotoxic compounds determined?
  • What are examples of traditional cytotoxic compounds?
  • Are the terms “cytotoxic” and “genotoxic” synonymous?
  • Do I need a dedicated manufacturing facility or equipment for cytotoxic compounds?
  • Can an occupational exposure limit (OEL) and acceptable daily exposure (ADE/PDE) value be established for a cytotoxic compound?

In addition, Dean Calhoun discusses events and happenings that are related to environmental, health, and safety in the life sciences industry. To listen to this podcast, click on the link above or below.

 

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http://potentcompoundsafety.com/2016/01/cytotoxic-compounds.html/feed 0 Our new podcast on “Mystery of Cytotoxic Compounds” is now posted on the affygility.com website. In this podcast, Dr. Joe Nieusma and Dean Calhoun, CIH discuss the following: What is a “cytotoxic compound?” How are cytotoxic compounds determined? Our new podcast on “Mystery of Cytotoxic Compounds” is now posted on the affygility.com website. In this podcast, Dr. Joe Nieusma and Dean Calhoun, CIH discuss the following: What is a “cytotoxic compound?” How are cytotoxic compounds determined? What are examples of traditional cytotoxic compounds? Are the terms “cytotoxic” and “genotoxic” synonymous? Do I need […] 27:58
Affygility Solutions on SnapChat http://potentcompoundsafety.com/2016/01/affygility-solutions-snapchat.html http://potentcompoundsafety.com/2016/01/affygility-solutions-snapchat.html#comments Wed, 13 Jan 2016 17:16:02 +0000 http://potentcompoundsafety.com/?p=2631 Getting ready to starting posting some serious sound-bites of EHS knowledge on SnapChat. Will be cover the basics of environmental, health and safety in the life science industry, as well as fun stuff regarding the world-wide travels of an EHS professional. Add Affygility through the username affygility or take a picture of the Snap code below:

affygility-snapchat-code

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Affygility Solutions encrypts its entire website for all visitors http://potentcompoundsafety.com/2015/07/affygility-solutions-encrypts-website-visitors.html http://potentcompoundsafety.com/2015/07/affygility-solutions-encrypts-website-visitors.html#comments Mon, 13 Jul 2015 02:56:07 +0000 http://potentcompoundsafety.com/?p=2623 Beginning today, Affygility Solutions will encrypt its entire website, making it extremely difficult for hackers, governmental agencies, and others to track the reading habits of people visiting the site. The added security will apply to all pages on the affygility.com domain.

“Here at Affygility Solutions, security and privacy for our site visitors has always been a top priority” says Dean M. Calhoun, CIH, President and CEO of Affygility Solutions “and while, our e-commerce portions of the site have always been encrypted, we recognize that many of our visitors are frequent business travelers and are accessing our site through airport and public WiFi hotspots. We want our visitors to know that their visits to our site, no matter where they connect, are protected.”

While encryption has long been the standard for finance and e-commerce sites, Affygility Solutions, as an industry leader, is the first environmental, health, and safety consulting firm to roll-out encryption for all its site visitors.

Most browsers will note the added security with a display icon depicting a small lock, in the web address bar. The secure affygility.com site will also begin with “https” instead of the former “http.” The type of encryption used by Affygility Solutions is known as SSL (secure sockets layer) which establishes a private connection between the website and the user, making spying or hijacking extremely difficult.

This encryption technology also has the potential to make online monitoring more difficult for governments with high levels of censorship and surveillance. When visitors go to a site using SSL, someone monitoring their traffic will only see the domain that they are visiting – not the specific page. Since Affygility Solutions has potent compound safety clients in over 30 different countries, this is of growing importance in protecting the privacy of our clients’ information.

For further information, please contact Affygility Solutions.

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Upcoming potent compound safety presentation by Affygility Solutions http://potentcompoundsafety.com/2015/06/potent-compound-safety-presentation-affygility-solutions.html http://potentcompoundsafety.com/2015/06/potent-compound-safety-presentation-affygility-solutions.html#comments Sun, 28 Jun 2015 23:58:07 +0000 http://potentcompoundsafety.com/?p=2619 The following is a list of the upcoming potent compound safety presentations by Affygility Solutions:

  • 4th Annual HPAPI Conference, Boston, MA, Monday, July 13th, 2015: Risk Management & Industrial Hygiene: Preventing Cross Contamination & Employee Exposures In The Context Of HPAPIs
  • CPhI Worldwide, Madrid, Spain, Tuesday, October 13th, 2015: Safe Handling of Potent Compounds.
  • 2015 ISPE Annual Meeting, Philadelphia, PA. Monday, November 9th, 2015: The Future of Pharma Manufacturing – The Next 100 Years

If you’re attending any of these conferences, please feel free to come up and introduce yourself. If you would like to schedule a private meeting, please complete the “contact us” form on our main website.

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Attending AIHce 2015? Follow Affygility on Twitter or Instagram http://potentcompoundsafety.com/2015/05/aihce-2015-affygility-twitter-instagram.html http://potentcompoundsafety.com/2015/05/aihce-2015-affygility-twitter-instagram.html#comments Wed, 13 May 2015 01:07:13 +0000 http://potentcompoundsafety.com/?p=2610 Attending the American Industrial Hygiene Conference and Exposition (AIHce) 2015 in Salt Lake City, May 30th through June 4th? Follow Affygility Solutions on Twitter or Instagram for deets on #secretbeerparty2.0. Want advance notice of the location? Then follow affygility on Snapchat (works on smartphones only, no desktop version). Don’t know how to use Snapchat, then go here: Snapchat Basics. This year’s party plans to be better than ever. If you don’t follow, you won’t know. Hook up with either Peter Burke or Dean Calhoun during the conference for a wristband. Time and location to be announced later. Wristbands only.

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Get your FREE ebook: Potent Compound Safety Handbook – A Guide to Working with Potent Compounds http://potentcompoundsafety.com/2015/04/potent-compound-safety-handbook-guide-working-potent-compoundsaff.html http://potentcompoundsafety.com/2015/04/potent-compound-safety-handbook-guide-working-potent-compoundsaff.html#comments Sat, 25 Apr 2015 16:24:31 +0000 http://potentcompoundsafety.com/?p=2600 Affygility Solutions is pleased to announce the availability of its latest FREE eBook: Potent Compound Safety Handbook – A Guide to Working with Potent Compounds. In this 18-page handbook in pdf format, we will cover the following topics:

  • The definition of “What is a Potent Compound?”
  • Getting your potent compound safety program started
  • Determining occupational hazard categories
  • Ten myths regarding PDEs, ADEs, and OELs
  • The future of OELs

To download this FREE eBook in pdf format click here.

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Affygility Solutions publishes IFTTT recipe for OEL Fastrac notifications http://potentcompoundsafety.com/2015/04/affygility-solutions-publishes-ifttt-recipe-oel-fastrac-notifications.html http://potentcompoundsafety.com/2015/04/affygility-solutions-publishes-ifttt-recipe-oel-fastrac-notifications.html#comments Mon, 13 Apr 2015 00:52:52 +0000 http://potentcompoundsafety.com/?p=2596 Now stay up to date and get instantly notified by email of the latest OEL Fastrac with ADE monographs that has been posted to the oelfastrac.com site! Affygility Solutions has published an IFTTT (If-this-than-that) recipe to make it easy. Just go to the link below to get the recipe:

https://ifttt.com/recipes/275270-sends-an-oel-fastrac-update-to-your-email

]]> http://potentcompoundsafety.com/2015/04/affygility-solutions-publishes-ifttt-recipe-oel-fastrac-notifications.html/feed 0 OEL Fastrac catalog listing now available as a RSS feed http://potentcompoundsafety.com/2015/03/oel-fastrac-rss-feed.html http://potentcompoundsafety.com/2015/03/oel-fastrac-rss-feed.html#comments Mon, 30 Mar 2015 02:12:40 +0000 http://potentcompoundsafety.com/?p=2585 Affygility Solutions is pleased to announce that its OEL Fastrac catalog listing is now available as a RSS (Really Simple Syndication) feed. Listed below is an example of the feed displaying that latest six occupational exposure limit (OEL) with ADE monographs. Click on the compound name heading to go directly to the specific OEL/ADE monograph product page.

  • Cyproterone acetate


    Cyproterone acetate is indicated for the management of patients with prostatic cancer 1) to suppress "flare" with initial lutenizing hormone releasing hormone (LHRH) analogue therapy, 2) in long-term palliative treatment where LHRH analogues or surgery are contraindicated, not tolerated, or where oral therapy is preferred, and 3) in the treatment of hot flushes in patients under treatment with LHRH analogues or who have been castrated. It is marketed under the trade name Cyprostat® 2), and is not approved in the United States. In addition, cyproterone acetate is used in combination with estradiol as an oral contraceptive and for the treatment for severe acne in women with symptoms of androgenization.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Cyproterone acetate is available for purchase for $597 USD.

  • Hydroxocobalamin


    Hydroxocobalamin is indicated for the treatment of cyanide poisoning and for treatment of anemia and vitamin B12 deficiency. Hydroxocobalamin binds cyanide ion in the plasma and is a form of vitamin B12.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Hydroxocobalamin is available for purchase for $597 USD.

  • Thebaine


    A drug that is derived from opium, which contains from 0.3-1.5% thebaine depending on its origin. It is an important intermediate in the biosynthesis of morphine alkaloids. The chemistry of oripavine and thebaine has been studied to synthesize opioid pharmaceuticals such as oxymorphone, naloxone and buprenorphine. Thebaine is used for pain.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Thebaine is available for purchase for $597 USD.

  • Calcium folinate


    Please note, this OEL/ADE monograph also applies to folinic acid (CAS RN 58-05-9).Calcium folinate is indicated for the treatment of colon cancer in combination with other agents and for leucovorin rescue from high dose methotrexate and folate deficiency induced anemia. Calcium folinate is also known as folinic acid, calcium folinate and citrovorum factor.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Calcium folinate is available for purchase for $597 USD.

  • Oripavine


    Oripavine is the major alkaloid of Papaver orientale. It is an important intermediate in the biosynthesis of morphine alkaloids. The chemistry of oripavine has been studied to synthesize opioid pharmaceuticals such as oxymorphone, naloxone and buprenorphine. Oripavine is a strong pain reliever, with analgesia comparable to morphine. However, oripavine is extremely toxic and has relatively low therapeutic value.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Oripavine is available for purchase for $597 USD.

  • Vecuronium bromide


    Vecuronium bromide is a muscle relaxant that facilitates both rapid sequence and routine insertion of a tube in the trachea (windpipe) during general anesthesia, and provides skeletal muscle relaxation during surgery or mechanical ventilation. Vecuronium bromide is a nondepolarizing neuromuscular blocking agent with a rapid to intermediate onset depending on dose and intermediate duration. It acts by competing for cholinergic receptors at the motor end-plate.

    Affygility Solutions has an occupational exposure limit (OEL) and control band assignment for this active pharmaceutical ingredient (API). This monograph also contains the acceptable daily exposure (ADE) value.

    The OEL Fastrac monograph for Vecuronium bromide is available for purchase for $597 USD.

If you wish to add the feed to a feed reader, here’s the link: http://affygility.com/oel/feed.xml

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